Pet Education

Browse our veterinary-reviewed Dog and Cat Illness Guide to learn more about pet health. Always talk to your veterinarian if you have a concern about your pet's symptoms or health.
Pet Assure allows pet owners to save on their pet's veterinary care, even pre-existing conditions. Click here to learn more.

Feline Cholangitis/Cholangiohepatitis


Bile is produced by the liver, stored in the gall bladder, and goes through the bile ducts into the intestines to digest fats.

Cholangitis is inflammation of the bile duct. Cholangiohepatitis is inflammation of the bile ducts, gall bladder, and liver. These two conditions usually occur simultaneously and are referred to as CCHS.

When any of these organs become inflamed, bile production decreases, and/or the bile cannot go through the ducts.

Left untreated, CCHS will cause liver failure.


CCHS can be classified as suppurative or nonsuppurative.

Suppurative CCHS is caused by a bacterial infection.

Nonsuppurative CCHS causes:


Suppurative signs are sudden and severe:

Nonsuppurative signs are chronic and general:


Your veterinarian will first test for other diseases that cause similar signs to CCHS. Some tests may include:

If your veterinarian suspects CCHS, some tests may include:


Most veterinarians will recommend the following treatments for cats with CCHS:

The rest of the treatment depends on the underlying cause.


If the cause is suppurative, then the best preventative is to avoid bacterial infection.


Suppurative: there is a good prognosis with prompt treatment, usually needed long-term.

Nonsuppurative: the prognosis depends on the severity. If the case is advanced, the prognosis is not so good.

Medically Reviewed by Sara Ochoa, DVM

Welcome Veterinarians

Pet Assure is the largest veterinary network in the U.S. with over 5,600 veterinarians.

Pet Assure powers DVM Network, a brand built to support our participating veterinary professionals and help them grow their practice.

Visit to learn more.