Pet insurance companies call it a pre-existing condition. I call it thrombocytopenia.

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Canine Thrombocytopenia

A platelet is a type of blood cell produced by the bone marrow that helps blood clot. If your dog gets a cut, the platelets go to the damaged blood vessels and clump together, sealing the leaking blood vessel.

Thrombocytopenia is a decrease of the platelets, in which causes increased bleeding and bruising.


The main cause is an autoimmune disease (the immune system attacks its own body). In this case, the immune system mistakenly thinks the platelets are enemies. The spleen removes platelets from the blood 10 times faster than normal.

Other causes may include:

  • Severe blood loss
  • Infections
  • Certain medications
  • Bone marrow not producing enough platelets
  • Bone marrow cancer, chemotherapy
  • Pancreatitis


The lower the platelet count, the more signs your dog will show. Some dogs may not show any signs, and thrombocytopenia will only be discovered during a routine exam.


  • Sudden, visible bruising
  • Nosebleeds
  • Blood in the urine and feces


In order to properly diagnose your dog with thrombocytopenia, your veterinarian may perform:

  • Blood tests: platelet count, complete blood count
  • Urinalysis
  • Bone marrow aspiration (using a thin needle to take a sample)
  • Tests on the immune system
  • Chest or abdominal x-rays: to check for underlying diseases


Your veterinarian may suggest the following treatment methods:

  • Blood transfusion: to stabilize your pet ifit had blood loss
  • Medications: to treat any underlying causes

If the cause is immune-mediated, you must stop the spleen from removing platelets. There are medications for this. In some cases, your dog may need surgery to remove the spleen.


There is currently no known prevention against this condition.


The prognosis depends on the cause. A mild cause has an excellent prognosis. A more severe cause, such as cancer, has a more guarded prognosis.

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